cefdinir eefpodoxime , cefprozil , ce£uroxime, cephalexin , and loracarbe£ when uged for therapy of uncomplicated t.TTIs due to E. coli, K. pneumotniae, and p. mirabilis. PARENTERAL therapy: cefazolin MIC of indicates resistance to parenteral 'Cultu»e, Urine COLOtW COUNT. Source. hesult: Result i 4/247016 PH PH Status: COLONIES/ML FINAL REPORT STAPffiLococcus SPECIES (COAGULASE. 2.2 ± 0.6 hours vs young: 1.8 ± 0.4 hours). Since cefdinir clearance has been shown to be primarily related to changes in renal function rather than age, elderly patients do not require dosage adjustment unless they have markedly compromised renal function (creatinine clearance 30 mL/min, see. Patients with Renal Insufficiency , above). Gender and Race. The results of a meta-analysis of. Intravenous vs oral administration. Vancomycin must be given intravenously (IV) for systemic therapy, since it is not absorbed from the intestine. It is a large hydrophilic molecule that partitions poorly across the gastrointestinal mucosa. Due to short half-life, it is often injected twice daily. The only approved indication for oral vancomycin therapy is in the treatment of pseudomembranous. Key Clinical Points Treatment of Acute Uncomplicated Appendicitis Patients with acute, localized, uncomplicated appendicitis (approximately 80% of all appendicitis cases) are candidates for appende.